＜書籍 Books＞
精神科医と診る精神疾患ミミック / 内科医と診る器質性精神病
石田 琢人 著
2025/2/28 発売開始
￥3,080 税込




書店・各種ネット通販で好評発売中
https://www.amazon.co.jp/dp/4498229649

【書籍紹介文】
精神症状をきたすが精神疾患ではない「精神疾患ミミック」という言葉は，内科臨床でなじみ深いと思います．
一方で，現在では正式な用語でないにもかかわらず「器質性精神病」は精神科臨床でよく使われます．

それぞれ似たような一群を表していますが，内科医と精神科医では見ている世界が大きく異なります．
ある側からすると，“原病のコントロール不良による病態や治療による有害事象は原則的に主科が診療すべき”と考えているかもしれません．
一方で別の側からは，“身体的な問題は身体を診る科が診療すべき”と譲らないかもしれません．

「器質疾患を除外しよう！」のスローガンから始まる精神科と内科のミスコミュニケーション．
それを回避するための方法論をぜひご覧ください．

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＜学術論文 Articles＞

Funayama M. Why physical restraints for fall prevention in psychiatric inpatients are medically unjustifiable. Psychiatry Clin Neurosci. 2025 Feb 24. doi: 10.1111/pcn.13807. Epub ahead of print. PMID: 39992013.

Koyama G, Nakano M, Takata T, Kuramochi S, Koreki A, Ishida T, Uchida H, Funayama M. Reversible dementia due to hyperthyroidism: Cognitive impairment, delusions, and agitation resolved with antithyroid treatment. J Neurol Sci. 2025 May 15;472:123474. doi: 10.1016/j.jns.2025.123474. Epub 2025 Mar 21. PMID: 40138854.

Nakano M, Funayama M, Takata T, Wakisaka R, Koyama G, Koreki A, Ishida T, Uchida H, Mimura M. Caution for psychiatrists: malignant hyperthermia risks with the anesthetic agent succinylcholine (Suxamethonium) during electroconvulsive therapy. BMC Psychiatry. 2024 Jun 4;24(1):411. doi: 10.1186/s12888-024-05846-5. PMID: 38834964; PMCID: PMC11149279.

Kudo S, Uchida T, Nishida H, Takamiya A, Kikuchi T, Yamagata B, Mimura M, Hirano J. Clinical characteristics and potential association to Parkinson's disease and dementia with Lewy bodies in patients with major depressive disorder who received maintenance electroconvulsive therapy: a retrospective chart review study. BMC Psychiatry. 2023 Apr 11;23(1):243. doi: 10.1186/s12888-023-04743-7. PMID: 37041471; PMCID: PMC10091570.

Kubo K, Takehara M, Hirata M, Huh S, Kawano S, Uchida H, Takeuchi H. Effects of Intravenous Hydroxyzine Versus Haloperidol Monotherapy for Delirium: A Retrospective Study. J Clin Psychiatry. 2025 Jan 6;86(1):24m15569. doi: 10.4088/JCP.24m15569. PMID: 39832341.

Kuramochi S, Yatomi T, Uchida T, Takeuchi H, Mimura M, Uchida H. Drug Combinations for Mood Disorders and Physical Comorbidities That Need Attention: A Cross-Sectional National Database Survey. Pharmacopsychiatry. 2022 May;55(3):157-162. doi: 10.1055/a-1744-6582. Epub 2022 Feb 4. PMID: 35120382.

Kurose S, Koreki A, Funayama M, Takahashi E, Kaji M, Ogyu K, Takasu S, Koizumi T, Suzuki H, Onaya M, Mimura M. Resting-state hyperperfusion in the whole brain: A case of malignant catatonia that improved with electric convulsion therapy. Schizophr Res. 2019 Aug;210:287-288. doi: 10.1016/j.schres.2019.05.042. Epub 2019 Jun 6. PMID: 31178364.

Ishida T, Shibahashi K, Sugai S, Abe D, Hamabe Y, Kashiyama T, Mimura M, Suzuki T, Uchida H. Development of a risk stratification scoring system for deep vein thrombosis upon psychiatric admission. J Psychosom Res. 2021 Aug;147:110540. doi: 10.1016/j.jpsychores.2021.110540. Epub 2021 May 31. PMID: 34102544.

Ishida T, Takahashi K, Sugiyama K, Hamabe Y, Mimura M, Suzuki T, Uchida H. How common is pulmonary embolism compared to acute myocardial infarction among patients with severe mental illnesses? Psychiatry Clin Neurosci. 2020 Apr;74(4):277-278. doi: 10.1111/pcn.12978. Epub 2020 Jan 27. PMID: 31930689.

Ishida T, Sugiyama K, Tanabe T, Hamabe Y, Mimura M, Suzuki T, Uchida H. Lower Proportion of Fatal Arrhythmia in Sudden Cardiac Arrest Among Patients With Severe Mental Illness Than Nonpsychiatric Patients. Psychosomatics. 2020 Jan-Feb;61(1):24-30. doi: 10.1016/j.psym.2019.08.005. Epub 2019 Aug 28.
PMID: 31607503.

Ishida T, Sakurai H, Watanabe K, Iwashita S, Mimura M, Uchida H. Incidence of deep vein thrombosis in catatonic patients: A chart review. Psychiatry Res. 2016 Jul 30;241:61-5. doi: 10.1016/j.psychres.2016.04.105. Epub 2016 Apr 30. PMID: 27156025.

Ishida T, Suzuki T, Watanabe K, Sakurai H, Uchida H, Mimura M. Prophylactic use of heparin for deep vein thrombosis in restrained psychiatric patients: a chart review. Gen Hosp Psychiatry. 2014 Nov-Dec;36(6):690-3. doi: 10.1016/j.genhosppsych.2014.06.007. Epub 2014 Jun 29. PMID: 25070076.

Ishida T, Katagiri T, Uchida H, Takeuchi H, Sakurai H, Watanabe K, Mimura M. Incidence of deep vein thrombosis in restrained psychiatric patients. Psychosomatics. 2014 Jan-Feb;55(1):69-75. doi: 10.1016/j.psym.2013.04.001. Epub 2013 Jul 9. PMID: 23845320.

Ishida T, Miyazaki K, Yukawa T, Yamagishi T, Sugiyama K, Tanabe T, Hamabe Y, Mimura M, Suzuki T, Uchida H. Etiology of out-of-hospital cardiac arrest in psychiatric patients: Chart review. Psychiatry Clin Neurosci. 2019 May;73(5):243-247. doi: 10.1111/pcn.12813. Epub 2019 Feb 6. PMID: 30588704.

Koreki A, Terasawa Y, Oi H, Mouri T, Takenaka A, Koizumi T, Onaya M, Yogarajah M, Critchley H, Nuruki A. Reduced sensory attenuation is related to aberrant interoceptive influences on intentional binding in schizophrenia. PCN Rep. 2025 May 2;4(2):e70106. doi: 10.1002/pcn5.70106. PMID: 40321471; PMCID: PMC12046975.

Koreki A, Terasawa Y, Nuruki A, Oi H, Critchley H, Yogarajah M, Onaya M. Altered sense of agency in schizophrenia: the aberrant effect of cardiac interoceptive signals. Front Psychiatry. 2024 Sep 25;15:1441585. doi: 10.3389/fpsyt.2024.1441585. PMID: 39386898; PMCID: PMC11461937.

Koreki A, Sado M, Mitsukura Y, Tachimori H, Kubota A, Kanamori Y, Uchibori M, Usune S, Ninomiya A, Shirahama R, Fujimoto A, Inabe K, Miyata H, Mimura M. The association between salivary IL-6 and poor sleep quality assessed using Apple watches in stressed workers in Japan. Sci Rep. 2024 Sep 30;14(1):22620. doi: 10.1038/s41598-024-70834-4. PMID: 39349506; PMCID: PMC11442746.

Koreki A, Ogyu K, Miyazaki T, Takenouchi K, Matsushita K, Honda S, Koizumi T, Onaya M, Uchida H, Mimura M, Nakajima S, Noda Y. Aberrant heartbeat-evoked potential in schizophrenia. Prog Neuropsychopharmacol Biol Psychiatry. 2024 Jun 8;132:110969. doi: 10.1016/j.pnpbp.2024.110969. Epub 2024 Feb 16. PMID: 38369098.

Koreki A, Mori H, Nozaki S, Koizumi T, Suzuki H, Onaya M. Risk of Nonalcoholic Fatty Liver Disease in Patients With Schizophrenia Treated With Antipsychotic Drugs: A Cross-sectional Study. J Clin Psychopharmacol. 2021 Jul-Aug 01;41(4):474-477. doi: 10.1097/JCP.0000000000001421. PMID: 34086626.

Koreki A, Garfkinel SN, Mula M, Agrawal N, Cope S, Eilon T, Gould Van Praag C, Critchley HD, Edwards M, Yogarajah M. Trait and state interoceptive abnormalities are associated with dissociation and seizure frequency in patients with functional seizures. Epilepsia. 2020 Jun;61(6):1156-1165. doi: 10.1111/epi.16532. Epub 2020 Jun 5. Erratum in: Epilepsia. 2020 Aug;61(8):1803. doi: 10.1111/epi.16658. PMID: 32501547; PMCID: PMC7737228.

Koreki A, Maeda T, Fukushima H, Umeda S, Takahata K, Okimura T, Funayama M, Iwashita S, Mimura M, Kato M. Behavioral evidence of delayed prediction signals during agency attribution in patients with schizophrenia. Psychiatry Res. 2015 Nov 30;230(1):78-83. doi: 10.1016/j.psychres.2015.08.023. Epub 2015 Aug 13. PMID: 26323167.

Funayama M, Koreki A, Takata T, Hisamatsu T, Mizushima J, Ogino S, Kurose S, Oi H, Mimura Y, Shimizu Y, Kudo S, Nishi A, Mukai H, Wakisaka R, Nakano M. Pneumonia Risk Increased by Dementia-Related Daily Living Difficulties: Poor Oral Hygiene and Dysphagia as Contributing Factors. Am J Geriatr Psychiatry. 2023 Nov;31(11):877-885. doi: 10.1016/j.jagp.2023.05.007. Epub 2023 May 22. PMID: 37286391.

Funayama M, Koreki A, Takata T, Kurose S, Hisamatsu T, Ono A, Yagihashi T, Mizushima J, Yagi Y, Ogino S, Oi H, Mimura Y, Shimizu Y, Kudo S, Nishi A, Mukai H. Differentiating autoimmune encephalitis from schizophrenia spectrum disorders among patients with first-episode psychosis. J Psychiatr Res. 2022 Jul;151:419-426. doi: 10.1016/j.jpsychires.2022.05.008. Epub 2022 May 13. PMID: 35597225.

Funayama M, Koreki A, Mimura Y, Takata T, Ogino S, Kurose S, Shimizu Y, Kudo S. Restrictive type and infectious complications might predict nadir hematological values among individuals with anorexia nervosa during the refeeding period: a retrospective study. J Eat Disord. 2022 May 5;10(1):64. doi: 10.1186/s40337-022-00586-x. PMID: 35513879; PMCID: PMC9074196.

Funayama M, Mimura Y, Takata T, Koreki A, Ogino S, Kurose S, Shimizu Y. Hypokalemia in patients with anorexia nervosa during refeeding is associated with binge-purge behavior, lower body mass index, and hypoalbuminemia. J Eat Disord. 2021 Aug 6;9(1):95. doi: 10.1186/s40337-021-00452-2. PMID: 34362446; PMCID: PMC8348865.

Funayama M, Mimura Y, Takata T, Koreki A, Ogino S, Kurose S. Body mass index and blood urea nitrogen to creatinine ratio predicts refeeding hypophosphatemia of anorexia nervosa patients with severe malnutrition. J Eat Disord. 2021 Jan 6;9(1):1. doi: 10.1186/s40337-020-00356-7. PMID: 33407855; PMCID: PMC7789160.

Funayama M, Takata T. Psychiatric inpatients subjected to physical restraint have a higher risk of deep vein thrombosis and aspiration pneumonia. Gen Hosp Psychiatry. 2020 Jan-Feb;62:1-5. doi: 10.1016/j.genhosppsych.2019.11.003. Epub 2019 Nov 9. PMID: 31734627.

Funayama M, Takata T, Koreki A, Ogino S, Mimura M. Catatonic Stupor in Schizophrenic Disorders and Subsequent Medical Complications and Mortality. Psychosom Med. 2018 May;80(4):370-376. doi: 10.1097/PSY.0000000000000574. PMID: 29521882; PMCID: PMC5959200.

＜資料 Documents＞

認知症の鑑別疾患 Differential Diagonsis of Dementia

2025年7月28日の研究会で発表した内容です。どの疾患が特に改善の可能性があるかについて、有益な情報も入っています。

This is the content of a presentation given at the July 28, 2025, research meeting on the differential diagnosis of dementia. It also includes useful information on which conditions are particularly likely to show improvement

https://drive.google.com/file/d/1W6Uf4YRl0HXdmOElp5bebYUkBrjHuLb5/view?usp=sharing